The Role of Adrenaline in Cardiac Arrest

To look at the survival benefit of adrenaline administration in cardiac arrest, a group of 8014 patients was examined from December 2014 to October 2017. The majority of patients were considered to have had a medical event as cause of the cardiac arrest. Of the enrolled patients, 4015 patients received adrenaline and 3999 received a placebo during the arrest. Results showed a significant increase in return of spontaneous circulation (ROSC) and a greater survival benefit at 30 days for the adrenaline group. However it should be noted that the neurological outcome in survivors of the adrenaline group was also worse than that of the placebo group.

Have a listen to the podcast on Rebel EM discussing the trial and results.